| Datum | Tijd | Thuisteam | Uitteam | Accommodatie | Plaats |
| 13-2-2022 | 14:30 | Germanicus 1 | WVV 1 | Sportpark de Pampert | COEVORDEN |
| 20-2-2022 | 14:00 | FVC 1 | Germanicus 1 | Sportpark Wiarda | LEEUWARDEN |
| 27-2-2022 | 14:30 | Germanicus 1 | GRC Groningen 1 | Sportpark de Pampert | COEVORDEN |
| 6-3-2022 | 14:00 | Noordster 1 | Germanicus 1 | Sportpark Oude Pekela | OUDE PEKELA |
| 13-3-2022 | 14:30 | Germanicus 1 | Heerenveen 1 | Sportpark de Pampert | COEVORDEN |
| 20-3-2022 | 14:00 | Roden 1 | Germanicus 1 | Sportpark v.v. Roden | RODEN |
| 27-3-2022 | 14:30 | Germanicus 1 | Hoogezand 1 | Sportpark de Pampert | COEVORDEN |
| 3-4-2022 | 14:00 | Gomos 1 | Germanicus 1 | Sportpark Schapendrift | NORG |
| 10-4-2022 | 14:30 | Germanicus 1 | SVBO 1 | Sportpark de Pampert | COEVORDEN |
| 18-4-2022 | 14:00 | Heerenveen 1 | Germanicus 1 | Sportpark Skoatterwâld | HEERENVEEN |
| 24-4-2022 | 14:30 | Germanicus 1 | Stadspark 1 | Sportpark de Pampert | COEVORDEN |
| 1-5-2022 | 14:00 | Jubbega 1 | Germanicus 1 | Sportpark ’t Heidefjild | JUBBEGA |
| 8-5-2022 | 14:30 | Germanicus 1 | FVC 1 | Sportpark de Pampert | COEVORDEN |
| 12-5-2022 | 19:30 | GRC Groningen 1 | Germanicus 1 | Sportpark Corpus Den Hoorn | GRONINGEN |
| 15-5-2022 | 14:30 | Germanicus 1 | VKW 1 | Sportpark de Pampert | COEVORDEN |
| 22-5-2022 | 14:00 | WVV 1 | Germanicus 1 | Sportpark WVV | WINSCHOTEN |
| 29-5-2022 | 14:30 | Germanicus 1 | Noordster 1 | Sportpark de Pampert | COEVORDEN |
